Sandra Caplan earned a B.F.A. at the University of Manitoba, Canada, where she studied painting and drawing with William Ashby McCloy, George Swinton, and Richard Williams, and an M.F.A. at Boston University, studying with David Aronson, Jack Kramer, and Reid Kaye. She studied at Yale University with Bernard Chaet, S. Silmann, and visiting artists John Schueler and Nicholas Carone.
She has had solo and participated in group exhibitions in museums, galleries and corporate spaces in Canada, the U.S., and Italy from 1961 to the present, the most recent being at the Palazzina Azzura in Ascoli Piceno, Italy and at the Kinnescope Gallery in New York.
She received grants and residencies from the Canada Council (Italy), Boston University, Yale University, Yale Norfolk, MacDowell, the Provincetown Workshop, the Woodstock Art Association, the Cooperstown Art Association, the Lenox School, and the Town School.
She has taught art in New York at the MOMA, the Brooklyn Museum, the Village Community School, the Lenox School, the Town School, the Horace Mann School, and the School of the National Academy of Design.
She has also taught art privately, in her studio at Westbeth, in New York City where she has been living and working since 1970. For the last 20 years she has also been living and working part of the year in Italy.